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Objective:To explore the value of low-dose CT in pregnancy with COVID-19.Methods:A retrospective analysis was performed on the clinical characteristics, laboratory tests, and chest CT findings of 12 pregnant women with COVID-19 diagnosed by nucleic acid testing in the Renmin Hospital of Wuhan University from January 20, 2020 to February 16, 2020. Two radiologists blinded to the reconstruction algorithm independently scored subjective image quality on a 5-point Likert scale. Image quality score ≥ 3 was acceptable in clinics. The CT radiation doses were recorded, including CT volume dose index (CTDI vol), dose length product (DLP), and effective radiation dose ( E). Two radiologists observed the distribution, shape, density, and other characteristics of lung lesions, and they also decided whether hilar, mediastinal lymphadenopathy, and pleural changed. Results:A total of 12 pregnant women with COVID-19, 8 had cough, 4 had fever, 2 had chest tightness, and 1 had dyspnea and diarrhea each. The CT image quality score of all patients was 3-4, with an average of 3.46, which fully met the clinical diagnosis requirements. The CTDI vol value was 1.13-4.31 mGy, with an average of 3.02 mGy. The DLP value was 34.48-75.29 mGy·cm, with an average of 55.48 mGy·cm. The Evalue was 0.48-1.05 mSv, with an average of 0.78 mSv. In all cases, chest CT examination showed abnormal manifestations after clinical symptoms, including unilateral lung lesions in 5 cases and bilateral lung lesions in 7 cases, 1 case of ground-glass opacity, 1 case of solidification, 7 cases of ground-glass and consolidation, 1 case of strip opacity, ground-glass, and consolidation and strip cable shadow coexisted in 2 cases. Conclusions:The application of low-dose CT scan in pregnant women with COVID-19 is completely feasible. CT mainly manifested as bilateral lung patchy and flaky ground-glass opacity with consolidation. Active and effective treatment can help recover and improve prognosis.
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OBJECTIVE: To analyze the inter-laboratory comparison results of occupational hygiene laboratories of Guangdong Province. METHODS: The 42 laboratories that continuously participated in the inter-laboratory comparison of occupational hygiene technical service institutions in Guangdong Province from 2014 to 2018 were selected as the research subjects Guangdong Occupational Health Test Center from 2014 to 2018 were selected by convenient sampling method. The data of detection of organic compounds, metal element, non-metal element in the workplace air, detection of metal element in biological materials, and the detection of free silica in dust were analyzed. The results were statistically analyzed by four-point robust statistical technique. RESULTS: From 2014 to 2018, a total of 1 205 items of sample detection results were submitted in these 5 years. The qualified rate of sample test was 92.4%(1 114/1 205) in these laboratories. The qualified rate of test of organics in workplace air, metals in workplace air, inorganic non-metals in workplace air, metals in biological materials and free silica in dust were 93.3%, 94.4%, 91.6%, 84.4% and 91.8% respectively. There was no significant difference in the qualified rate of sample test between the laboratories in the Pearl River delta in Guangdong Province and the laboratories in other regions the laboratories in other regions(92.8% vs 89.6%, P>0.05). There was no significant difference in the qualified rate of sample test among the occupational disease prevention and treatment institute, center for disease control and prevention and private laboratories(93.1% vs 93.6% vs 89.0%, P>0.05). Among the 91 unqualified items, 35 items were │z score of inter-laboratory(z_B)│≥ 3(38.5%), 40 items were │z score of within-laboratory(z_w)│≥ 3(44.0%), and 16 items were│z_B│≥ 3 and │z_w│≥ 3(17.6%). CONCLUSION: The laboratories in Guangdong Province that participated in the inter-laboratory comparison of occupational health test for 5 consecutive years have a relatively high level of occupational health testing, and the test results are accurate.
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OBJECTIVE: To analyze the results of inter-laboratory comparison among occupational hygiene laboratories. METHODS: A convenient sampling method was used. The laboratories participating in the inter-laboratory comparison organized by the Guangdong Occupational Health Test Center from 2013 to 2017 were selected as study subjects. The data of detection of organic compounds, metal element, inorganic non-metal element in workplace air, detection of metal element in biological materials, and detection of free silica in dust were analyzed. The results were statistically analyzed by four-point robust statistical technique. RESULTS: A total of 615 laboratories(times) participated in the comparison, and 2 785 items of sample detection results were submitted from 2013 to 2017.Among them, a total of 2 484 items were tested qualified and the sample test qualified rate was 89.2%. The test qualified rates of organics in workplace air, metals in workplace air, inorganic nonmetals in workplace air, metals in biological materials and free silica in dust were 91.1%, 92.0%, 86.6%, 80.4% and 85.0%, respectively. The sample test qualified rates of the laboratories in different regions from high to low were: the laboratories Pearl River Delta region in Guangdong Province, the laboratories in non-pearl river delta region in Guangdong Province and the laboratories outside of Guangdong Province were 91.6%, 87.2% and 72.6%(P<0.01), respectively. The sample test qualified rate of the public laboratories was higher than that of the private laboratories(90.3% vs 87.0%, P<0.05). CONCLUSION: The accuracy of the occupational hazard factor test in the participating laboratories needs to be improved. It is necessary to further strengthen the investment, supervision and management to non-pearl river delta region laboratories and private laboratories in Guangdong Province.
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OBJECTIVE: To summarize and analyze the diagnostic ideas of new occupational lung tumors in Guangdong Province.METHODS: According to the Law of the People′s Republic of China on the Prevention and Control of Occupational Disease and the GBZ 94-2002 Diagnostic Criteria of Occupational Cancer, the key diagnostic points of 6 new occupational lung tumors diagnosed in Guangdong Province from 2010 to 2011 were analyzed. RESULTS: There were 9 cases of 6 new kinds of new occupational tumors were diagnosed in Guangdong Province in 2010-2011. The cases included 3 occupational lung cancer of coke oven workers, 2 occupational lung cancer caused by asbestos, 1 occupational mesothelioma caused by asbestos, 1 occupational lung cancer caused by arsenate, 1 occupational lung cancer caused by chromate salt, and 1 occupational lung cancer caused by asphalt. During the process, the diagnosis was based on the principles of the comprehensive analysis and the attribution diagnosis, combined with occupational history, occupational disease hazard exposure history, clinical data and auxiliary examination results. If the patients were diagnosed with a primary tumor, the patients′ exposure history to occupational carcinogens should be tracked, traced and confirmed, and the diagnosis should be confirmed by referring to the list of occupational carcinogens and literature reports of the International Labor Organization, and not limited to only the personnel in a particular industry. CONCLUSION: During the diagnostic process of occupational tumors, attention should be paid to confirm the exposure history of occupational carcinogen. The key is to determine the exposure of corresponding occupational carcinogen, the route and the time of exposure and the incubation period.
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OBJECTIVE: To investigate the individual external dose level of medical radiation staffs in Guangzhou City.METHODS: The medical radiation staffs of Guangzhou City who conducted individual dose monitoring at Guangdong Province Hospital Center for Occupational Diseases Prevention and Treatment from 2008 to 2014 were selected as study subjects by convenient sampling method.Their individual dosage monitoring data were analyzed.RESULTS: A total of 17 754 person-times were monitored in 7 years.The annual collective effective dose was 10 621.1 person·mSv and the median per capita annual effective dose was 0.21 mSv/a.The per capita annual effective dose in 2008-2012 showed an increasing trend each year( P < 0.05),peaked in 2012,and then decreased in 2013 and 2014( P < 0.05).The per capita annual effective dose of radiology staffs in level Ⅱ medical institutions was higher than that of level Ⅲ medical institutions,level Ⅰ medical institutions and those below level Ⅰ( P < 0.01).The per capita annual effective dose of radiation staffs in level Ⅲ medical institutions was higher than level Ⅰ medical institutions and those below level Ⅰ( P <0.01).The effective monitoring rates of radiation staffs monitored for 4 cycles every year increased with time from 2008 to 2014( P < 0.01).The effective monitoring rate increased with the hospital level( P < 0.01).The per capita annual effective dose of the staffs in radiological diagnosis department was lower than that of clinical nuclear medicine,radiotherapy and interventional radiology( P < 0.01).CONCLUSION: The radiation dose of medical radiation staffs in Guangzhou City was within the national standard limit.Protection should be focused on the the staffs in secondary hospitals,clinical nuclear medicine,radiotherapy and interventional radiology.
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OBJECTIVE: To evaluate the technical level and ability of the detection of free silica in dust in occupational health technical service institutions of Guangdong Province through inter-laboratory comparison. METHODS: The interlaboratory detection of free silica in dust in 55,61,58 and 66 occupational health technical service institutions were carried out and compared in 2012-2015. The results were statistically analyzed by four points robust statistical technique,and the relative deviation between the laboratory test results and the Median of them was used as the auxiliary evaluation index of the laboratory's technical ability. RESULTS: The stable coefficient of variation(CV) of samples with free silica content > 20. 00% was less than 5. 00%,and the stable CV of samples with free silica content ≤20. 00% was more than5. 00%. The qualified rate in 2012-2015 were 89. 09%,81. 97%,77. 59% and 81. 82%,respectively. There was no statistical difference(P > 0. 05) in the annual reference between private and non-private institutions compared to the qualified rate in 2012-2015. There was no statistical difference(P > 0. 05) in the qualified rate of the institutions in the Pearl River Delta region and in the non-triangular regions of the Pearl River Delta in 2012-2015. CONCLUSION: Comparison of the detection technology service ability in the detection of free silica in dust should be conducted to improve its technical service quality.